Description
Thyroid Stimulating Hormone (TSH) is a glycoprotein
hormone secreted by the pituitary gland and regulates
the synthesis/release of T3 and T4 by thyroid gland.
TSH has two subunits, namely alpha and beta. The
alpha subunit is similar to the alpha subunit found in
LH, FSH, and hCG glycoprotein hormones. However,
the beta subunit is specific and differs from hormone to
hormone. The serum TSH measurement is one of the
most important tools in the diagnosis of thyroid
disorders. Increased serum TSH is an early and
sensitive indicator of decreased thyroid reserve and
overt primary hypothyroidism. Decreased of TSH levels
is an indicator of TSH-independent hyperthyroidism
(Graves disease). The sensitivity of this ELISA test is
0.05 µIU/mL.
